As we learnt in statistical mechanics, a natural way of describing many-component physical systems is through a statistical description. For example, rather than following the dynamics of all $10^{23}$ molecules of a gas, it is more informative to look at the average properties of such ensemble of molecules, that end up being related with thermodynamic quantities like temperature, pressure and so on.
Physicist's analysis of complex systems builds up in this approach of statistical mechanics. The idea is that microscopic degrees of freedom evolve in an stochastic manner and one seeks extracting average/ensamble properties that provide information at the macroscopic level (of the system as a whole).
The origin of fluctuations in complex systems depend on the particular phenomena under study and on the level of description of the model. Two typical frameworks are diffusion and pure jumping processes. On the one hand, diffusion (SDEs with white/colored noise) emerge when the description of the system is done at a mesoscopic level. The noise in this description represents our ignorance of the particular set of microscopic events, which are coarse-grained into the noise term. On the other hand, jumping process (Poisson noise) is used when one tries to model at a finer-microscopic description. The noise here represents the intrinsic randomness of the evolution of the system at microscopic level. Van Kampen's system expansion is a technique that allows deriving mesoscopic descriptions (diffusions) from microscopic ones (pure jumping processes)