Not entirely sure I've understood the question, but this might be of use:
(1) DataTables has a ColReorder plugin.
http://datatables.net/extensions/colreorder/
In the link above, you can select a column with your mouse and then drag the column to a different position in the table.
In another example of using the ColReorder plugin, you can predefine your
column order, as stated on the datatables site:
http://datatables.net/release-datatables/extensions/ColReorder/examples/predefined.html
ColReorder provides the ability to specify a column ordering which is
not that of the HTML (which typically you will want) through the
parameter oColReorder.aiOrder. This is an array of integers with the
column ordering you want.
(2) I believe you could also make use of aoColumnDefs and mDataProp if your data was an array of objects. (also see http://datatables.net/usage/columns)
...
"aoColumnDefs": [
{ "mDataProp": "FirstName", "aTargets": [ 0 ] },
{ "mDataProp": "LastName", "aTargets": [ 1 ] },
{ "mDataProp": "LicenseNumber", "aTargets": [ 2 ] }
],
...