IUnknown::QueryInterface on this interface pointer to obtain one of the following: IPersist, IPersistStream, IPersistStreamInit or other IPersist* interfaces. If you are lucky to get one, then GetClassID method will get you the CLSID class identifier (alternate option is IProvideClassInfo and IProvideClassInfo::GetClassInfo).
Note that this kind of information does not have to exist. An interface pointer can be valid without having CLSID on the class implementing it.
UPD. If the main goal is to recognize your own implementation on the provided interface ("Is the provided ICanvasFont the instance of my own MCanvasFont class, or it is something different?"), then the easiest yet efficient way is to implement some extra private interface on the class. If your querying it succeeds, then you recognize the instance. Provided no marshaling takes place, you can possibly even static_cast back to original C++ pointer.