You're looking for numpy:
import numpy as np
x = np.array([-0.22258, 0.50889, -0.35733, -0.22992, -0.26910])
For instance:
x = np.array([-0.22258, 0.50889, -0.35733, -0.22992, -0.26910])
y = np.array([10,9,8,7,6])
>>> x/y
array([-0.022258 , 0.05654333, -0.04466625, -0.03284571, -0.04485 ])
>>> x+y
array([ 9.77742, 9.50889, 7.64267, 6.77008, 5.7309 ])
>>> x-y
array([-10.22258, -8.49111, -8.35733, -7.22992, -6.2691 ])
and LOTS of much more complicated numerical computation capabilities. The documentation says it all.
As a side note, since it seems you're a MATLAB user, you can take a look at this NumPy for MATLAB users conversion table, I used it quite a bit to get me started when I was translating an algorithm from MATLAB to Python.