In a comment (in response to a question from me), you shared that dump(largenumber) on the offending value returns
Typ=2 Len=8: 45,50,56,53,52,48,46,48
From the outset, that means that the data stored on disk is invalid (it is not a valid representation of a value of number data type). Typ=2 is correct, that is for data type number. The length (8 bytes) is correct (we can all count to eight to see that).
What is wrong is the bytes themselves. And, we only need to inspect the first and the last byte to see that.
The first byte is 45. It encodes the sign and the exponent of your number. The first bit (1 or 0) represents the sign: 1 for positive, 0 for negative. 45 is less than 128, so the first bit in the first byte is 0; so the number is negative. (So far this matches what you know about the intended value.)
But, for negative numbers, the last byte is always the magic value 102. Always. In another comment under your original question, Connor McDonald asks about your platform - but this is platform-independent, it is how Oracle encodes numbers for permanent storage on any platform. So, we already know that the dump value you got tells us the value is invalid.
In fact, Connor, in the same comment, gave the correct representation of that number (according to Oracle's scheme for internal representation of numbers). Indeed, just the last byte is wrong: your dump shows 48, but it should be 102.
How can you fix this? If it's a one-off, just use an update statement to replace the value with the correct one and move on. If your table has a primary key, let's call it id, then find the id for this row, and then
update {your_table} set largenumber = -50...... where id = {that_id};
Question is, how many such corrupt values might you have in your table? If it's just one, you can shrug it off; but if it's many (or even "a handful") you may want to figure out how they got there in the first place.
In most cases, the database will reject invalid values; you can't simply insert 'abc' in a number column, for example. But there are ways to get bad data in; even intentionally, and in a repeatable way. So, you would have to investigate how the bad values were inserted (what process was used for insertion).
For a trivial way to insert bad data in a number column, in a repeatable manner, you can see this thread on the Oracle developers forum: https://community.oracle.com/tech/developers/discussion/3903746/detecting-invalid-values-in-the-db
Please be advised that I had just started learning Oracle at that time (I was less than two months in), so I may have said some stupid things in that thread; but the method to insert bad data is described there in full detail, and it was tested. That shows just one possible (and plausible!) way to insert invalid stuff in a table; how it happened in your specific case, you will have to investigate yourself.
select dump(largenumber) from {your_first_table}and show us what it comes back with. Thedumpfunction works on all expressions (of any data type) and it shows exactly what is stored on disk, in raw form. That may give us some clues.