With apologies to ncoghlan:
expanded_bits = [
0b00000000000000000000000000000000,
0b00000000000000000000000011111111,
0b00000000000000001111111100000000,
0b00000000000000001111111111111111,
0b00000000111111110000000000000000,
0b00000000111111110000000011111111,
0b00000000111111111111111100000000,
0b00000000111111111111111111111111,
0b11111111000000000000000000000000,
0b11111111000000000000000011111111,
0b11111111000000001111111100000000,
0b11111111000000001111111111111111,
0b11111111111111110000000000000000,
0b11111111111111110000000011111111,
0b11111111111111111111111100000000,
0b11111111111111111111111111111111,
]
Then just index this list with the nibble you want to transform:
>>> bin(expanded_bits[0b1011])
"0b11111111000000001111111111111111"