Well, it's sort of possible:
(defmacro voodoo [s]
(let [env (zipmap (map (partial list 'quote) (keys &env))
(keys &env))]
`(if-let [v# (~env (symbol ~s))]
v#
(throw (RuntimeException. "no such local")))))
...and now we can do weird stuff like this:
user> (defn example [s]
(letfn [(foo [x] {:foo x})
(bar [x] {:bar x})]
((voodoo s) :quux)))
#'user/example
user> (example "foo")
{:foo :quux}
user> (example "bar")
{:bar :quux}
user> (example "quux")
; Evaluation aborted.
user> *e
#<RuntimeException java.lang.RuntimeException: no such local>
That "Evaluation aborted" means an exception was thrown.
You could also replace the throw branch of the if in voodoo with (resolve (symbol ~s)) to defer to the globals if no local is found:
(defmacro voodoo [s]
(let [env (zipmap (map (partial list 'quote) (keys &env))
(keys &env))]
`(if-let [v# (~env (symbol ~s))]
v#
(resolve (symbol ~s)))))
...and now this works with definition of example as above (though note that if you are experimenting at the REPL, you will need to recompile example after redefining voodoo):
user> (defn quux [x] {:quux x})
#'user/quux
user> (example "quux")
{:quux :quux}
Now, this is an abuse of Clojure's facilities which one would do well to try to do without. If one cannot, one should probably turn to evalive by Michael Fogus; it's a library which provides an "eval-with-locals" facility in the form of an evil function and a couple of utilities. The functionality seems to be well factored too, e.g. something like the ~(zipmap ...) thing above is encapsulated as a macro and evil there appears to be almost a drop-in replacement for eval (add the env parameter and you're good to go). I haven't read the source properly, but I probably will now, looks like fun. :-)