I usually do not post an answer when there are no efforts shown by the OP, but this is one of those unique cases where the question itself is interesting, the solution is a bit complex, and it can help a lot of future visitors. Dependent dropdowns are a very common query, and there is a clean way to handle them in Excel 365 without using VBA or INDIRECT.
You can achieve this using the new dynamic array functions like UNIQUE() and FILTER().
Here is how I would set it up.
As per your image, your database is in B2:E32, and your dropdowns are in H3:K3.

Now, create helper formulas. For example, in columns M to P.
M3 -> =IFERROR(SORT(UNIQUE(FILTER($B$3:$B$32,$B$3:$B$32<>""))),"")
N3 -> =IFERROR(SORT(UNIQUE(FILTER($C$3:$C$32,$B$3:$B$32=$H$3))),"")
O3 -> =IFERROR(SORT(UNIQUE(FILTER($D$3:$D$32,($B$3:$B$32=$H$3)*($C$3:$C$32=$I$3)))),"")
P3 -> =IFERROR(SORT(UNIQUE(FILTER($E$3:$E$32,($B$3:$B$32=$H$3)*($C$3:$C$32=$I$3)*($D$3:$D$32=$J$3)))),"")

Screenshot for the first one is shown above. Similarly do it for the rest.
Next set your Data Validation lists as follows:
H3 -> =M3#
I3 -> =N3#
J3 -> =O3#
K3 -> =P3#

Screenshot for the first one is shown above. Similarly do it for the rest.
Explanation of # used in Data Validation List:
The # symbol in Excel is called the spill range operator. It tells Excel,
Use the entire range of cells that this formula spills into.
If we take the example of A3, we have =M3#
This means Refer to all the cells that are part of the spilled array from M3, however many rows that happens to be.
So if next month your database grows and there are five more clients, your formula automatically spills further down, and the dropdown still captures the new names, because M3# expands with it.
In short:
M3 = just the top cell of the spill.
M3# = the entire spilled result of that formula.
In Action

INDIRECT()then you have to use a helper sheet. A sheet which will hold filter formulas in each row, so when you will select an item in your calculation sheet, then the helper sheet's formula will return depended values. And second dropdown will refer that calculated cells using cell refence with hash (#) operator.